Like Paxlovid, other antiviral medications can stop the breakdown of atorvastatin. Your healthcare provider will likely have you stop taking atorvastatin until you finish Paxlovid. This can cause atorvastatin to build up, raising your risk of side effects. But the ritonavir in Paxlovid stops the breakdown of atorvastatin in the body. Paxlovid (nirmatrelvir/ritonavir) is an antiviral medication authorized to treat COVID-19 in certain people. So, having a small glass every now and then shouldn’t be a problem. In rare cases, this can lead to rhabdomyolysis (a breakdown of muscle that can cause harm to your kidneys).īut, this interaction usually is only a problem when you drink a lot of grapefruit juice (about 5 cups or 1 liter per day or more). This can raise your risk of side effects, like muscle pain or weakness. Grapefruit and grapefruit juice can increase the amount of atorvastatin in the body. Keep in mind that this list doesn’t include all possible atorvastatin interactions. Here, we'll review some notable ones you should know about. So, which atorvastatin interactions should you be most aware of? 11 atorvastatin interactions to know aboutĪtorvastatin has many possible interactions. It works by blocking the production of cholesterol in the liver.īut while effective, atorvastatin has many interactions with other medications. Atorvastatin can help lower the risk of heart disease by lowering cholesterol and triglyceride (a type of fat) levels. Millions of people take this statin medication for high cholesterol. Atorvastatin (Lipitor) is one of the most prescribed medications in the U.S.
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